This handbook provides guidance for designing and implementing a monitoring and evaluation (M&E) system. The guidance supports and complements CRS's global M&E standards. The global standards represent the agency's commitment to high quality M&E as a key component of program quality, and this handbook provides step-by-step guidance for operationalizing this commitment. Each topic includes its own set of standards, which emphasizes the key messages and quality considerations relevant to the topic. Whereas the global M&E standards are high-level overaching commitments, the standards in this handbook provide practical and quality-control considerations specific to individual components of an M&E system.