This Compendium is a pioneering collection of case studies describing area-based approaches to urban challenges (2010-2019). The case studies were sourced from multiple agencies, collected by the Urban Settlements Working Group of the Global Shelter Cluster, co-chaired by Catholic Relief Services, IMPACT Initiatives and InterAction. The case studies documented here are in responses to both humanitarian crises and developmental challenges and from a mix of contexts such as rapid onset Natural disasters, Conflict induced crisis and effects of Rapid urbanisation. The case studies are organised in three sections according to the administrative scale of project / initiative. From City level scale (C) to District/ Borough scale (D) and to Neighbourhood / ward level (N).