This practical field guide brings together lessons learned from Oxfam‟s past interventions in the prevention and control of cholera, and other related guidance. The aim is to provide a quick, step-by-step guide to inform cholera outbreak interventions and ensure public health programmes that are rapid, community-based, well-tailored, and gender and diversity aware. The guidelines given here are not comprehensive – they have been designed to be used together with existing Oxfam and WASH (water, sanitation, and hygiene) cluster public health guidelines. The guidelines will enable both public health teams and programme managers to undertake necessary preparations to prevent cholera outbreaks from occurring and to respond effectively when they have occurred. They have been specifically designed to fit the cholera outbreak curve, depicting key activities in each critical phase before, during and after outbreak. They can also be adapted to suit other water- and sanitation-related outbreaks, such as Typhoid, Hepatitis E, and dysentery, as well as other WASH-related diarrhoeal outbreaks.